Herein, we examined the phosphorylation profile of sMyBP C in mouse and human fast twitch skeletal muscles

2013 - 04 - 15

We used Flexor Digitorum Brevis (FDB) isolated from young (2 months old) and old (14 months old) wild type and mdx mice, and human Abductor Hallucis (AH) and gastrocnemious muscles carrying the DA 1 mutations. Our results indicate both constitutive and differential phosphorylation of sMyBP C in aged and diseased muscles.

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